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Both drugs, known as cox-2 inhibitors, have already been shown to inhibit the growth of tumors that depend on the cox-2 enzyme, as happens with some prostate and breast cancers.
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The drugs wortmannin and LY294002 are widely used in the laboratory to block activation of Akt by inhibiting PI3 kinase.
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Mobic is co-marketed by Boehringer Ingelheim Corp.
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